SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65522ae22a5e8796193cc226fbb4390170071668814fae6d5852fd2950e663c1' 
  AND token = 'F8iBs6r+ktVILvzlYNJxlaXnSgR+7A9bzHh1DCITRK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

Explain
id select_type table type possible_keys key key_len ref rows Extra
1 SIMPLE Impossible WHERE noticed after reading const tables