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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d1292917282f99a8bc0855b6d9188493047e8d85d4cd9732abc1a7e8435c594' 
  AND token = '8F4oNTxCJpMCPKVNvU5BkPPLScO3j7dh7FQ2ZCUkIEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables