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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65726f3b26fa3e36e525b25fecf54550d385f66cc2ea90b3c5ccdf7e66a5510b' 
  AND token = '0Frp5OgE7BUj7XQOM7Joreyh6oQsvwpd2t7yY71aSOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables