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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46d21bfb719bcc2b6bee235c686275a885b9ae1a84d1f3abb98986fbf91a8c1a' 
  AND token = '/jIPEh2jsUWybGrPqKATs1pOErHJbpcXETxUdgHjKlA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables