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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2266954bff18c6ead717d2696a4fb934c9e8fd8e84610689ff3c8dc610306cb6' 
  AND token = 'aEyrJjZSWcObbxfW2qLWj4i4PKHPCBSksPqc7BO8FbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables