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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '293c9610f00437b022c44d464442cb490a15afdf163168ba2dbe159707de7521' 
  AND token = 'EFqUq8rQeJjBbmq0T3ZEA9yS9YIRvJd5PdcVeOKMzOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables