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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b5c43d182c4e975b9a0649cabaa7626caf9ebff1bdffd246b83b0992a84c5b6' 
  AND token = 'sOrSYeQRwpqTD8Mq40A4RpQ440EXz8pdosJY7pG2aac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables