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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd21a1994f4cbc53e7497cad0a49e6fb43316a37626243152af29839bf52858f8' 
  AND token = 'TAtQGvGFdAWpxQW0s6ZUJhEgTx85aY6InhOWpAc26kE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables