SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11145163c0cef3a5de31316b38ceb842d55ea5d0dd3f1c5d25ccfaa3aad33960' 
  AND token = 'jxL+EciEymMp5Aq0L/eqIZAbWeXi0HwJa08umahWL3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

Explain
id select_type table type possible_keys key key_len ref rows Extra
1 SIMPLE Impossible WHERE noticed after reading const tables