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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00f61555cc36b7bce2ca0ff051d8f48172284ce1890e13a6763d5d50e3227ae5' 
  AND token = 'CLPnl+tmBnsjh5QsEmAHMI5xpKJ2lKSlipni+G5Ed0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables