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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '048f36352031dbb9c65c4c6004d6ee5bbc40d66d06caede1f55e0e52f6975f3d' 
  AND token = 'Vn/FiCCei68jAsWehPMiEJ0C1Wfs3baVaVKjWlsdvr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables