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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b115e4c49dc6b6a079973a9cda71b70f6d441a35998c2ca70a2045cade852357' 
  AND token = 'lKydPJ4OG5XxdPE6Gi5VVTzRnJyfze2QcAaYy49IHOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables