SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed01e5e520c62306ba991fbb3b911b862554ea6b73d9ad42021427c61d9fd79b' 
  AND token = 'KzVkUq80EENyMTmUT+FUFNr861yU4wcSfcZ8ZPjDL7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

Explain
id select_type table type possible_keys key key_len ref rows Extra
1 SIMPLE Impossible WHERE noticed after reading const tables