SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '221db6067b965a749e40d8c9edbaff3b45bdf6072f7476b6c9352d167c33afd5' 
  AND token = 'JVwRW/YnFZiECWMImstDsragYMB8hTO8tsGgGf09fcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

Explain
id select_type table type possible_keys key key_len ref rows Extra
1 SIMPLE Impossible WHERE noticed after reading const tables