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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cd7c050320e826a5bab109bf9509e41e19c6c8af06be5cc1ffb7ec868fdcaf5' 
  AND token = 'R4TvAmulRRWasDftZvI7ZyQtEKZV4OrXhRXoMANFul0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables