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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eafd437e2ae8e6180786be6e63750f15a0dd487199fdcb90f56fb4748550255' 
  AND token = 'E3KUkO7F3dA09l25HmDMooWSUCWIWQ2Zv3mWkE9OTFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables