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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22dc341af9fe9f5243d629a0982ba8458c88fa70edd287bfe2d3daece1cc1e46' 
  AND token = 'HFbUAvxB9gmkG0g7PRm1ktIvW585Atjs6XchvMpvwtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables