SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f8ac382643fb7181b3fcde2d5d18f4de40a040d46d9fc02397660c67450e68d' 
  AND token = 'lgxZYPaebx/UN7wM5HWwc/pzP5fIfU8jTPmhncpmxKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

Explain
id select_type table type possible_keys key key_len ref rows Extra
1 SIMPLE Impossible WHERE noticed after reading const tables