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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d651ba063e6f00d11eda14cf261a226442d3810b21a1da5eb58b232e74e36f5' 
  AND token = 'c6joNQqZNbAVnKvlQ5zm3iO0dwWycuZgLz9uDfLubRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables