SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ade221726d0875001a80899d0f9d5a6fe97e6194f0ef1adc078821c988e1555b' 
  AND token = 'NM+lYXKz8HV2gzaQa2rYQfuVQrgWEx91Dr4qWH+udFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

Explain
id select_type table type possible_keys key key_len ref rows Extra
1 SIMPLE Impossible WHERE noticed after reading const tables