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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43b5f7de564449de29959fa6c6b1e0d757539d942995d9ab26e6b7268a07d10b' 
  AND token = 'PNi4CJjYWyqkYlvCfktUd4oDJMkVemo8rPz4HA1bSZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables