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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6448ef888bbea375d8b3540332cff7dd9fcfe1a00b4c1f5b22d3c8854a70a59' 
  AND token = 'YNUiJ1ah50XfaAlkcLLKE1tn1SUzy0qQmOpaEn5JrKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables