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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e8a458f3c27724d53128f5c6228d64fe3b51e5799cf8ec15fdd78846632edfd' 
  AND token = 'SgplOAF54zlOKR3EiniW307cTsOlNp8o5RC2dhE1yxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables