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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7622922fcf745b918a29689e2bc164bc6f44f36a2055c809b0e34432bbb21db' 
  AND token = 'bsp0fwViVKKotj8e6JK5P9lBZysGgx9RgeKQI5rLcyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables