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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ed1c391de4e3fb1012e997efcb4c950bd7ffba454bf1c491278bc4c3b43d7a2' 
  AND token = 'e175KK7ZsDzX9OAf5gbqAj8FJR4wL1sxrtqStHkvsmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables