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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a9a5894accff87f327f1aa618c223ea3f241db93352a13bea263ae80e0f747d' 
  AND token = 'vyHfrOaqC9CfQzWtf2NhQdE0QyTayI5xpMiSMAeXeek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables