SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a207b5930b05ab1325509e03caae459e38064c34a5681a4fbd0ed87bfa6c743' 
  AND token = 'RMVb63CStX8UcpIukJenELzGmcPBxcbNOTdaaXIZmjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

Explain
id select_type table type possible_keys key key_len ref rows Extra
1 SIMPLE Impossible WHERE noticed after reading const tables