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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8a5ab390eab9de2ee374623054375ba908343568045dfcfa62db8d7c6894aa5' 
  AND token = 'K7DXtrr618GTd3WI2uyiu0egKEySuN72wxnqAd7tXiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables