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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a7895027426b7b572cd11616306c3e971b36e92bd3f2ede5c6481d3fa8c120' 
  AND token = '8pmQED5aB8Q2wY2cdcz5VQ0XDmEaUykA48VaEQwcQaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables