SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aef01328bf7f96de041f7900149bc3937c452537bee527a221dc812f20185f2' 
  AND token = 'LWuFd5CfpipzizYeAPeF1xZTc1eFbb1hQAyZF19VvpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

Explain
id select_type table type possible_keys key key_len ref rows Extra
1 SIMPLE Impossible WHERE noticed after reading const tables