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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '426573bc51a6f7bfc7109ef02b446f4ea01619d1416128e9fa9466c4f4da1df2' 
  AND token = 'u+SytdvZ96CguHqZa39j97u0QPQvIW7s8E4HKDNRf44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables