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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '280e1f1e63b435c837d35c7344a0fdd5433507413399628197aec91721d5ad34' 
  AND token = '7BsrKxFlgllyZvx3gnINhYjjt6fwksmMSaXXyYBxB3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables