SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '066ec0b2ca3ce597a26ab5086362c472116d99eec6b018d36b5cb5ffd582f0bb' 
  AND token = 'nPlThH3W9e4zA29u75dp1IW72hmmJAIBv678/eVsgTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

Explain
id select_type table type possible_keys key key_len ref rows Extra
1 SIMPLE Impossible WHERE noticed after reading const tables