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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ea1b4f2b4af38575abe11107e577d535b70f2181cf5be85a5737e0c7571c09b' 
  AND token = 'PXgK1d1D0sO8uCCLWPl9aWo3WcZ8BKtGmykFMtAWKEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables