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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb3073f0812e353500153cd6b99964b0e5940650be787e891d992c4eb6d1f17' 
  AND token = 'RMu27Ep4Z618viQ8qwiUSTukllUDqN9z8qjClQNA1O0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables