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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0729698b4f6045e09714fc8e5f80e1d871867ace72001377492f8903e9ab2043' 
  AND token = '1WNYyMwIZRWU4cjxv69L02k1rKLudZfavF5ivADRWOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables