SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05f50032ba1a45e1109e0c0ef69deb8c92b9862c482f3a8c42f7b9bc8ab311fa' 
  AND token = 'VZQBNYxSrFM+oZdC9juUNaY1nMlDg1ha/OgLuNtlaAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

Explain
id select_type table type possible_keys key key_len ref rows Extra
1 SIMPLE Impossible WHERE noticed after reading const tables