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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '879a9956e7703d6dcc4dc52cfa8fd0fbed9046c28823221dbe40316f60bb18e8' 
  AND token = 'Io6Lou/nl/Wso78+9ce2QGZM9+uWyi02OQHzwZ7Wv0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables