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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef8f7a3fcd8d980b3719eb258f4aa97f9961b9dbc9bda0ec1d2e46925ddb280a' 
  AND token = 'CdVBzgmmg21k9FXU7jDrnUvnBw1hRR0y2R/F6xrxoJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables