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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cf39a1b40387e90e2d222a3bf435704b6c80716ee08ae5a03e90e4719b28e54' 
  AND token = 'Reno5zCkY1nK1DlNc8fy9dHibVJ3JssWnvRdHE7CzJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables