SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c00bc023a212d229e2de5344d9a3adcd00fd61b9f04b35a05955c06565a207a' 
  AND token = 'UJGQ5JIR6rFt19ff/AAdauU23srYxdjYHhuhiv7c0gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

Explain
id select_type table type possible_keys key key_len ref rows Extra
1 SIMPLE Impossible WHERE noticed after reading const tables