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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1943d54028f4348996ba06a4ed58639c09c6a506f478c1a306613aae008f15d' 
  AND token = 'P0c68LTDQyQfeWs4ZNwT8iaFDDLPslgdD8dOSN2YGBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables