SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '357b39e0c7ebe25a386dd7c4dba9f58cd58ce66e3e384c177fb3693504072009' 
  AND token = 'u74cIEPRpcvat1Gnh/l8dn1j2Sy2jQPKRfamszTPvK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

Explain
id select_type table type possible_keys key key_len ref rows Extra
1 SIMPLE Impossible WHERE noticed after reading const tables