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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43d385d4d43fea7e80c8c02c5f888ee72772e04f0940e52c307ae48f7e27fb69' 
  AND token = 'qldEkMOyYI2HgZ0ZeNzoJV0SS4EUPwB7cQFUmlY17yY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables