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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b21dab7726c077bdbfbbac24bad1716680c63ec9fec5f2bda6e50719b4298d' 
  AND token = 'MEGN8FPC6hLyLk7v9VWh03xSJ61KmXBkpdrTAQEmVCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables