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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fa4dc11256571ef58484863b3ff0834ac0e5966e1766e8e744b682c84e27657' 
  AND token = 'JZ8SjUJBPeO7lRMjdMyrW0k6tyF7UIIHmXiLfMGfgkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables