SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b22163130f9b4ae57f732703d8d458adf56d312b9c6aa05fdc4f12a6601df4ee' 
  AND token = 'vDfqDvGcWjz8uKvNu+BLFkwEdoLtE+nzW1K9nEqKoHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

Explain
id select_type table type possible_keys key key_len ref rows Extra
1 SIMPLE Impossible WHERE noticed after reading const tables