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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad57c7d4c579272a1e87fbf7b876f7ff49e316c2d20c75e47c3af4f236e3e725' 
  AND token = 'QUd5nvI2xV86bTDr9MqrRGkRWv8Lwp6T5eKi6eG2IlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables