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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ebe039506bf81c315e57c2a8549ad56044f435ebc03ff4e787c95df6f134473' 
  AND token = 'R4HAnrketnV30Ave+WG57luN3X38zascfPb7B3usr0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables