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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0495564c9348f37042c465301bea6aad8c8b53b075a1e22c92667b231810bfac' 
  AND token = '7ZPYAiEVbYLiKz17Qgq6RefSdlY1yrhp8Z5iWZ6VM5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE								Impossible WHERE noticed after reading const tables